Past Leach Lectures YEAR NAME PRESENTATION TITLE 2024 David Craik Discovery and applications of cyclotides in medicine and agricultur 2023 Juliet Gerrard Proteins through the ages - my long and winding road 2022 Leann Tilley Seeing is believing: From cellular machinery to molecular movies to malaria therapies 2021 Mike Lawrence Celebrating insulin’s 100th anniversary: from crystals to cryoEM 2020 Jennifer L. Martin Me and my shadow CV 2019 Eleanor Dodson The Joy of Seeing - in Honour of Dorothy Hodgkin 2018 Raymond Norton Venom peptides as drugs: the long and winding road 2017 Marilyn Anderson Evolution, function and applications of plant defensins 2016 Bruce Kemp My 40 years of kinases: The importance of serendipity 2015 Eric Reynolds Phosphopeptides, proteases, a secretion system and oral health - a journey in dental research 2014 Anne Dell Glycoproteomic strategies: Exploring the glyco in glycoprotiens 2013 Stephen Kent Reimagining the natural protein world through total chemical synthesis 2012 Brian Matthews Protein crystallography: Getting in on the ground floor 2011 Robin Carrell How serpins raise our blood pressure, dormice survive and Australians thrive 2010 Edward Baker Serendipity and discovery: structure, assembly and stability of Gram-positive baterial pilli 2009 Colin Masters Aß oligomers as tractable targets for Alzheimer s disease diagnostics and therapeutics 2008 Peter E. Wright Exploring the energy landscape: Disorder, dynamics, and protein function 2007 David de Krester The highly conserved proteins, the activins and follistatin, exhibit actions from reproduction to inflammation and tissue repair 2006 Elizabeth Blackburn Telomeres and telomerase in human health and disease 2005 T. Jack Martin PTHrP, from cancer hormone to multifunctional protein 2004 John Wallace The biotin-dependent enzymes: their structures, their functions and their challenges 2003 Robin Anders Vaccinating against malaria with recombinant proteins: How important is protein conformation? 2002 Richard Perham Multifunctional Enzymes and Swinging Arms: From Genes to Catalytic Machines 2001 Colin Ward Relationships Between the Insulin Receptor Family and Other Proteins 2000 Russell Doolittle Reconstructing History with Protein Sequences 1999 Roger Y. Tsien Imaging and Manipulating Protein Interactions and Gene Expression in Individual Cells 1998 Geoffrey Tregear Relaxin: Understanding the Structure is Easier than Elucidating Biological Function 1997 Nicholas Hoogenraad Molecular Chaperones: Mediators of Protein Structure and Function 1996 Leroy Hood Joining the DNA and Protein Worlds 1995 Donald Metcalf Biochemical Aspects of Haemopoietic Regulators – a View from the Wings 1994 Jose N. Varghese Three-dimensional Structures of Barley (1-3, 1-4)-ß- and (1-3)-ß-Glucanases 1993 Edmond H. Fischer Protein Tyrosine Phosphatases 1992 Adrienne E. Clarke Molecular Genetics of Self-incompatibility in Flowering Plants 1991 Robert Huber Serine and Cysteine Proteases and their Natural Inhibitors. Structures and Implications for Function And Drug Design 1990 Anthony W. Burgess Identification and Design of Functional Motifs in Polypeptide Growth Factors 1989 J. Mitchell Guss Blue Copper Proteins – Structures, Predictions and Fictions 1988 Nicos A. Nicola Biological and Receptor-binding Specificities of Colony-stimulating Factors 1987 Peter M. Colman The Three-dimensional Structure of a Complex of Influenza Virus Neuraminidase and an Antibody at 3Å Resolution 1986 Robert L. Baldwin Salt Bridge and Helix dipole Interactions Controlling α-helix Stability
